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作者对年龄自6月～19岁的37例性腺发育不全综合症或其它类型原发性性腺功能低下患者血浆LH和FSH浓度的基础水平,及LRF的诱发的变化进行测定。所有患者的性发育均为幼稚型,且未接受过性甾体治疗,按年龄分为四组,将其促性腺激素基础值及其对LRF的反应与同年龄正常儿童作比较。 第一组6/12～46/12岁4例,平均LH基础浓度是3.2±0.4毫微克/毫升,明显高于同年龄对照组;经LRF刺激后LH浓度明显升高且大于对照组,平均FSH基础浓度较同年龄正常女孩高7倍,FSH的反应亦明显高于对照组;值得注意的是4岁
The authors determined the basal level of plasma LH and FSH concentrations in 37 gonadal dysgenesis syndromes or other primary hypogonadal conditions aged 6 months to 19 years and the changes induced by LRF. All patients were naïve and did not receive any sex steroid treatment and were divided into four groups by age. Baseline gonadotropin values and their responses to LRF were compared with those of normal children of the same age. The first group of 6/12/126 years old in 4 cases, the average basal LH concentration of 3.2 ± 0.4 ng / ml, was significantly higher than the same age control group; after stimulation by LRF LH concentration was significantly higher than the control group, the average FSH basal concentrations were 7 times higher than those of normal girls of the same age, and the response of FSH was also significantly higher than that of the control group; it is worth noting that the 4-year-old