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我们总结了三年半时间内急性心肌梗塞住院患者40例,在急性期用过消心痛者共32例,未用者8例。临床观察、病死率两者的差异无显著性,但用药者病情经过稳定,心律失常发生率明显减少。我们认为:①消心痛对心肌氧供的改善,包括冠状动脉及小冠状动脉扩张,更重要的,能降低左心室的前负荷及其舒张终未压,从而降低心肌耗氧量;②减少心律失常的发生;但是,③可能反射地使交感活性部分衰退及迷走神经张力增高,血压下降。我们认为对急性心肌梗塞的治疗,在没有血流动力学监测的条件下,如急性心肌梗塞头几天,动脉血压过低,不宜应用此药,而血压正常或偏高者,用此药似有一定裨益。
We summarized 40 hospitalized patients with acute myocardial infarction in three and a half years, 32 patients who had used heartburn in the acute phase, and 8 patients who did not use it. Clinical observation, mortality no significant difference between the two, but the patient’s condition after treatment, the incidence of arrhythmia was significantly reduced. We think: ① Xiao Xiao Tong on myocardial oxygen supply, including coronary and small coronary artery dilation, more importantly, can reduce the left ventricular preload and diastolic pressure, thereby reducing myocardial oxygen consumption; ② reduce the heart rate However, ③ may reflex partial decline in sympathetic activity and increased vagal tone, blood pressure decreased. We believe that the treatment of acute myocardial infarction, hemodynamic monitoring in the absence of conditions, such as the first few days of acute myocardial infarction, arterial pressure is too low, should not be used in this medicine, and blood pressure is normal or high, with this drug Have some benefits.