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由于米糠甲醇提取物可以抑制促癌物TPA诱发的炎症,故对其活性成分进行了筛选。 小鼠TPA诱发炎症试验:小鼠耳廓内、外涂布TPA 1μg诱发炎症,在涂布TPA前30min在同一部位涂布受试药物。以袖珍厚度量规测量涂布TPA 6h后(肿胀最显著时)
Because the methanol extract of rice bran can inhibit the inflammation induced by the promoter TPA, its active ingredients were screened. Induction of inflammation by TPA in mice: 1 μg of TPA was applied to the inside and outside of the ear to induce inflammation, and the test drug was applied to the same site 30 minutes before TPA coating. After 6 hours of coating TPA measured with pocket thickness gauge (the most significant swelling)