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含钙尿石中,80%为草酸钙或含有磷酸钙的混合结石。草酸钙溶解是一个限制性扩散的过程,其溶解速度与尿石的体表面积密切相关,pH 值在3~8之间对其影响甚小。震波碎石后可能有尿石残留,但其表面面积已显著增加.采用经皮肾造瘘术使对残留尿石进行化学溶解成为可能。为此,作者在体外实验中研究了钙离子螯合剂溶解草酸钙的动力学过程,并比较了不同螯合剂在不同浓度及 pH 条件下的溶石作用.
In calcium-containing uroliths, 80% is calcium oxalate or a mixed stone containing calcium phosphate. Calcium oxalate dissolution is a limiting diffusion process, the dissolution rate is closely related to the body surface area of uroliths, pH value of 3 to 8 have little effect on it. After the shock wave lithotripsy may have urinary residue, but its surface area has been significantly increased. The use of percutaneous nephrostomy to make residual urinary chemical dissolution possible. To this end, the authors in vitro experiments to study calcium ion chelator dissolve the kinetics of calcium oxalate, and compare different chelating agents in different concentrations and pH conditions of the role of the stone.