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目的 :通过横断面调查了解透析患者发生左心室肥厚 (LVH)的危险因素及其与血容量的关系。方法 :通过无创性方法 (Xitron 4 2 0 0生物阻抗分析仪 )分别测量我院 73例血透患者、4 6例腹膜透析患者透析前后血容量(ECW )变化和心脏形态学改变 (超声心动图 ) ,并设立 18例慢性肾衰竭患者和 16个正常人作为对照组。结果 :血液透析患者、腹膜透析患者、慢性肾衰竭患者及对照组左心室肥厚的发生率分别为 6 8%、5 6 %、39%和 0 % ,与对照组相比 ,这些患者的nECW均明显升高 (P <0 .0 0 1)。同时LVH与高血压、nECW、红细胞压积均呈显著相关关系 (P <0 .0 5 )。结论 :透析患者LVH的发生率较高 ,与高血压、红细胞压积和血容量密切相关。提示容量超负荷是引起透析患者和慢性肾衰竭患者高血压、LVH的关键因素
Objective: To investigate the risk factors of left ventricular hypertrophy (LVH) in dialysis patients and its relationship with blood volume through cross-sectional investigation. Methods: The hematocrit values of 73 hemodialysis patients and 46 peritoneal dialysis patients before and after hemodialysis were measured by noninvasive method (Xitron 4200 bioimpedance analyzer) before and after hemodialysis (ECW) and cardiac morphological changes (echocardiography ) And set up 18 patients with chronic renal failure and 16 normal subjects as control group. RESULTS: The rates of left ventricular hypertrophy in hemodialysis patients, peritoneal dialysis patients, chronic renal failure patients and controls were 68%, 56%, 39% and 0%, respectively. Compared with the control group, the nECW Was significantly higher (P <0. 001). At the same time LVH and hypertension, nECW, hematocrit showed a significant correlation (P <0. 05). Conclusion: The incidence of LVH in dialysis patients is high, which is closely related to hypertension, hematocrit and blood volume. Tip capacity overload is caused by dialysis patients and patients with chronic renal failure hypertension, LVH key factor