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目的采用正交试验法优选三黄桃葛胶囊的提取工艺。方法采用L(934)正交试验设计,以葛根素、总蒽醌和毛蕊异黄酮苷为评价指标,通过综合评分优选三黄桃葛胶囊的提取工艺。结果提取次数对试验结果有显著意义(P<0.05),加水倍数和提取时间则无显著意义,综合考察各因素的影响,确定最佳提取工艺为加6倍量水,回流提取3次,每次1 h。结论本试验方法简单稳定,对三黄桃葛胶囊的生产工艺具有一定的指导和参考意义。
Objective To optimize the extraction process of Sanhuang peach capsule by orthogonal test. Methods The orthogonal design of L (934) was used in this study. Puerarin, total anthraquinone and calycosin were used as evaluation indexes to optimize the extraction process of Sanhuang peach capsule. The number of extraction results was significant (P <0.05). There was no significant difference in water addition times and extraction time. Comprehensively considering the influence of various factors, the optimal extraction process was determined by adding 6 times the amount of water and extracting three times by reflux Times 1 h. Conclusion The test method is simple and stable, and has some guidance and reference significance for the production technology of Sanhuang peach capsule.