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目的:分析孟鲁司特联合布地奈德治疗小儿哮喘的临床疗效。方法:以双盲法对我院2014年3月-2016年3月内接诊的814例哮喘患儿随机分为对照组、观察组,均407例,对照组给予布地奈德治疗,观察组在此基础上加以孟鲁司特治疗,分析两组肺功能、不同时间点病情改善情况。结果:观察组、对照组治疗后肺功能较治疗前改善显著(p<0.05)且治疗后观察组肺功能较对照组改善明显(p<0.05);观察组治疗后不同时间点(1周、3周、8周、12周)病情较对照组改善明显(p<0.05)。结论:孟鲁司特联合布地奈德治疗小儿哮喘的临床疗效显著,值得应用。
Objective: To analyze the clinical efficacy of montelukast combined with budesonide in the treatment of pediatric asthma. Methods: A total of 814 cases of asthma admitted to our hospital from March 2014 to March 2016 were randomly divided into control group, observation group, and 407 cases. The control group was treated with budesonide. The observation group On this basis to montelukast treatment, analysis of lung function in two groups, at different time points to improve the situation. Results: After treatment, the lung function of the observation group and the control group improved significantly (p <0.05) and the lung function of the observation group improved significantly compared with the control group after treatment (p <0.05); the observation group at different time points after treatment (1 week, 3 weeks, 8 weeks, 12 weeks) than the control group improved significantly (p <0.05). Conclusion: The clinical efficacy of montelukast combined with budesonide in the treatment of pediatric asthma is significant and worthy of application.