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[目的]探讨宫颈神经内分泌癌的诊断、治疗和预后因素。[方法]回顾性分析2011年1月至2015年12月南京医科大学附属肿瘤医院收治的30例宫颈神经内分泌癌患者的临床资料。[结果]分期、淋巴结转移、血清神经元特异性烯醇化酶水平与总生存时间密切相关(P<0.05),而肿瘤浸润深度、脉管内癌栓、肿瘤直径、治疗方式对总生存时间无明显影响(P>0.05)。[结论]宫颈神经内分泌癌是一种罕见的妇科恶性肿瘤,预后差。分期、淋巴结转移能够影响预后。血清神经元特异性烯醇化酶水平能够作为监测预后的指标。
[Objective] To investigate the diagnosis, treatment and prognosis of cervical neuroendocrine carcinoma. [Methods] The clinical data of 30 patients with cervical neuroendocrine carcinoma admitted to Affiliated Tumor Hospital, Nanjing Medical University from January 2011 to December 2015 were retrospectively analyzed. [Results] Staging, lymph node metastasis and serum neuron-specific enolase levels were closely related to the overall survival time (P <0.05), while the depth of tumor invasion, intratracheal intubation, tumor diameter and treatment mode had no significant effect on the overall survival time Influence (P> 0.05). [Conclusion] Cervical neuroendocrine carcinoma is a rare gynecological malignant tumor with poor prognosis. Staging, lymph node metastasis can affect the prognosis. Serum neuron-specific enolase levels can be used as an indicator of prognosis.