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目的探讨纳洛酮治疗肺性脑病的临床疗效。方法将60例轻中度肺性脑病患者及42例重度肺性脑病患者随机分为治疗组及对照组,治疗组在常规治疗基础上加用纳洛酮3～6mg加入250ml5%葡萄糖水中静脉滴注,1次/d。结果轻中度患者治疗组有效率明显高于对照组,P<0.05,重度患者治疗组有效率与对照组无明显差异性P>0.05。结论纳洛酮在轻中度患者治疗中有较好疗效,重度患者疗效差。
Objective To investigate the clinical efficacy of naloxone in the treatment of pulmonary encephalopathy. Methods Sixty patients with mild to moderate pulmonary encephalopathy and 42 patients with severe pulmonary encephalopathy were randomly divided into treatment group and control group. The treatment group was given naloxone 3 ~ 6mg on 250ml 5% glucose water in routine therapy Note, 1 time / d. Results The effective rate of mild to moderate treatment group was significantly higher than that of the control group, P <0.05, the effective rate of the treatment group was no significant difference compared with the control group (P> 0.05). Conclusion Naloxone has a good effect in the treatment of mild to moderate patients, and the curative effect of severe patients is poor.