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目的:1.通过观察促排周期患者卵巢过度刺激综合征(OHSS)的发生率的不同,以探讨与OHSS发生相关的临床因素,以指导临床早期预防治疗。方法:1.选择符合纳入标准的224例需行促排卵治疗助孕的周期作为研究对象,观察OHSS病人与非OHSS病人两组在一般情况(年龄、BMI、体质状态、不孕年限等)、基础疾病状态(PCOS、EMS等)、促排治疗周期基础内分泌状况(E2、LH/FSH等)、基础B超情况(双侧卵巢大小及AFC等)及促排周期药物的选择及剂量(CC/LE、Gn用量等)等方面的差异,以筛查出其中有意义的指标,指导临床用药,早期预防OHSS的发生。结论:与非OHSS患者相比,OHSS患者在过敏体质、PCOS病史、AFC、HCG日血清E2水平、口服促排卵药物的选择、Gn的用量等方面有显著性差异(P<0.05)。
Objective: To observe the different incidence of ovarian hyperstimulation syndrome (OHSS) in ovulation-promoting cycle to explore the clinical factors related to the occurrence of OHSS to guide the early prevention and treatment of clinical. 224 cases of ovulation-assisted ovulation-assisted pregnancy that meet the inclusion criteria were selected as the research object to observe the general situation (age, BMI, constitutional status, duration of infertility, etc.) between OHSS patients and non-OHSS patients, (PCOS, EMS, etc.), basal endocrine status (E2, LH / FSH, etc.), basal B-status (ovarian size and AFC, etc.) / LE, Gn dosage, etc.) to screen out some of the meaningful indicators, to guide clinical medication, early prevention of OHSS. CONCLUSIONS: OHSS patients have significant differences (P <0.05) in allergic constitution, PCOS history, AFC, serum E2 level on HCG day, choice of oral anovulatory drug, and Gn dosage compared with non-OHSS patients.