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对１８例老年糖尿病肠病患者和２２例糖尿病无肠病者的血小板聚集、血栓素Ｂ２（ＴＸＢ２）和６－酮－前列腺素Ｆ１α（６－ｋｅｔｏ－ＰＧＦ１α）进行测定，并且与健康老年人比较。结果表明：肠病组血小板聚集率和肠病组、无肠病组血浆ＴＸＢ２、ＴＸＢ２／６－ｋｅｔｏ－ＰＧＦ１α比值均明显高于健康人组（Ｐ＜０．０１），而６－ｋｅｔｏ－ＰＧＦ１α则明显降低（Ｐ＜０．０１）。肠病组血小板聚集率、ＴＸＢ２及ＴＸＢ２／６－ｋｅｔｏ－ＰＧＦ１α比值变化较无肠病组更为明显（Ｐ＜０．０１）。这提示血小板功能亢进和血栓素Ａ２（ＴＸＡ２）与前列环素（ＰＧＩ２）间平衡失调可能在老年糖尿病肠病的发病过程中起着一定作用。
Platelet aggregation, thromboxane B2 (TXB2) and 6-keto-PGF1α in 18 elderly patients with diabetic enteropathy and 22 patients without diabetes were measured and compared with healthy controls . The results showed that the ratio of platelet aggregation and the ratio of TXB2 and TXB2 / 6-keto-PGF1α in the enteropathy and enteropathy groups were significantly higher than those in the healthy group (P <0.01), while the ratio of 6-keto-PGF1α Was significantly lower (P <0.01). Intestinal platelet aggregation rate, TXB2 and TXB2 / 6-keto-PGF1α ratio changes more significantly than the group without enteropathy (P <0.01). This suggests that impaired platelet function and imbalance between TXA2 and PGI2 may play a role in the pathogenesis of diabetic enteropathy.