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目的:探讨阿莫西林、克拉霉素、奥美拉唑三联短程疗法治疗消化性溃疡的临床效果。方法:将我院2011年3月~2015年12月收治的60例消化性溃疡患者,随机分为对照组和观察组,对照组采用奥美拉唑治疗,观察组采用阿莫西林、克拉霉素、奥美拉唑三联短程疗法治疗,分析两组治疗效果及不良反应发生情况。结果:治疗后,观察组总有效率96.7%,HP根除率为90.0%;对照组总有效率86.7%,HP根除率为80.0%。两组根治率、总有效率经统计学分析,差异有统计学意义(P<0.05)。结论:采用阿莫西林、克拉霉素、奥美拉唑三联疗法治疗消化性溃疡,疗效优于奥美拉唑治疗,HP根治率高,不良反应少,值得临床推广应用。
Objective: To investigate the clinical effect of amoxicillin, clarithromycin and omeprazole triple therapy in the treatment of peptic ulcer. Methods: Sixty patients with peptic ulcer admitted to our hospital from March 2011 to December 2015 were randomly divided into control group and observation group. The control group was treated with omeprazole. The observation group was treated with amoxicillin, Su, omeprazole triple short-term treatment, analysis of the two groups of treatment and adverse reactions. Results: After treatment, the total effective rate was 96.7% in the observation group and 90.0% in the HP group. The total effective rate was 86.7% in the control group and 80.0% in the HP group. The two groups of cure rate, the total effective rate by statistical analysis, the difference was statistically significant (P <0.05). Conclusion: Amoxicillin, clarithromycin, omeprazole triple therapy for the treatment of peptic ulcer, the effect is better than omeprazole treatment, HP cure rate is high, less adverse reactions, worthy of clinical application.