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目的:探讨米非司酮联合桂枝茯苓胶囊应用于子宫肌瘤治疗的可行性及安全性。方法:76例子宫肌瘤患者随机分为两组,对照组予以米非司酮单独治疗,治疗组加入桂枝茯苓胶囊联合治疗,完成治疗后观察疗效。结果:治疗组总有效率(84.2%)显著高于对照组总有效率(71.1%),组间差异有统计学意义(P<0.05);通过降低患者血生殖激素水平及改变血液流变学情况,两种治疗方法最终有效缩小子宫肌瘤体积,显著改善患者月经量增多、经期延长和贫血症状,且治疗组疗效优于对照组(P<0.05)。结论:米非司酮联合桂枝茯苓胶囊可协同治疗子宫肌瘤,效果较好,且安全性较高。
Objective: To investigate the feasibility and safety of mifepristone combined with Guizhi Fuling capsule in the treatment of uterine fibroids. Methods: 76 cases of uterine fibroids were randomly divided into two groups, the control group were treated with mifepristone alone, the treatment group with Guizhi Fuling capsule combined treatment, the completion of treatment after treatment. Results: The total effective rate (84.2%) in the treatment group was significantly higher than that in the control group (71.1%). There was significant difference between the two groups (P <0.05). By reducing the level of blood reproductive hormones and changing the blood rheology The two treatment methods effectively reduce the volume of uterine fibroids, significantly improve the patient’s menstrual volume, prolonged menstrual flow and anemia symptoms, and the treatment group than the control group (P <0.05). Conclusion: Mifepristone combined with Guizhi Fuling capsule can treat uterine fibroids synergistically, which has good effect and high safety.