CoCl2·6H2O催化合成3,4-二氢嘧啶-2-酮衍生物

• 作 者: 杨玲 郭延红 路军 白银娟
• 机 构: 西北大学化学系,延安大学化学系,西北大学化学系,西北大学化学系 陕西西安710069,新疆塔里木农垦大学文理学院,新疆阿拉尔843300,陕西延安716000,陕西西安710069,陕西西安71006
• 出 处: 化学研究与应用
• 发表日期: 2002年06期
• 关键词: Biginelli反应 六水合氯化钴 3 4二氢嘧啶2酮

dihydropyrimidinones derivatives were synthesized in high yields by one pot three component Biginelli condensation from aldehyde, β keto ester and urea in ethanol,while cobalt chloride hexahydrate was used as a catalyst.This modified Biginellis reaction not only makes the reaction period short,the operation simple,but also gives high yields.

dihydropyrimidinones derivatives were synthesized in high yields by one pot three component Biginelli condensation from aldehyde, β keto ester and urea in ethanol, while cobalt chloride hexahydrate was used as a catalyst. This modified Biginellis reaction not only makes the reaction period short, the operation simple, but also gives high yields.