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目的探讨小儿急性白血病(AL)发病年龄、性别、患病时间、就诊季节、临床类型及临床表现。方法对在我科住院的60例白血病患儿临床资料进行回顾性分析,所有病人均经过骨髓细胞学检查确诊AL。结果坚持1疗程VDLD方案化疗的18例ALL,其中完全缓解13例,部分缓解4例,未缓解1例。采用DA方案化疗的17例ANLL,1疗程后缓解9例,2疗程后缓解5例,未缓解3例。结论小儿急性白血病的患病年龄、就诊季节有一定的规律性,临床类型和临床表现复杂多样,临床医师必须提高对AL的诊断与鉴别诊断能力,才能尽早诊断AL。
Objective To investigate the age, sex, duration of illness, treatment season, clinical type and clinical manifestations of childhood acute leukemia (AL). Methods The clinical data of 60 leukemia children hospitalized in our department were retrospectively analyzed. All patients were confirmed by bone marrow cytology. Results Adhere to a course of treatment of VDLD chemotherapy in 18 cases of ALL, of which 13 cases were completely relieved, partial remission in 4 cases, 1 case without remission. 17 cases of ANLL treated with DA regimen, 9 cases were relieved after 1 course, 5 cases were relieved after 2 courses and 3 cases were not relieved. Conclusions The age at onset of acute leukemia in children and the regularity of treatment during the treatment season are complex. The clinical types and clinical manifestations of the patients are complex and diverse. Clinicians must improve the ability of diagnosis and differential diagnosis of AL in order to diagnose AL as soon as possible.