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目的对比研究超声诊断与肝活检对慢性乙型肝炎诊断的应用价值。方法 80例慢性乙型肝炎患者,均接受超声诊断、肝活检检查,对比两种检查技术诊断效果。结果通过肝活检病理诊断发现,肝硬化患者16例(20.00%),轻度慢性乙型肝炎患者28例(35.00%),中重度慢性乙型肝炎患者36例(45.00%);超声诊断结果显示,正常者5例(6.25%),肝硬化患者17例(21.25%),轻度慢性乙型肝炎患者26例(32.50%),中重度慢性乙型肝炎患者32例(40.00%),与肝活检病理诊断结果比较,差异无统计学意义(P>0.05)。超声诊断的敏感度为93.75%,准确度为87.50%。结论肝活检诊断能准确反映病变性质与程度,可作为临床诊断慢性乙型肝炎金标准;而在慢性乙型肝炎的临床检查中,应用超声诊断具有高度敏感性与精准性,能有效避免误诊与漏诊,可作为慢性乙型肝炎无创检查首选。
Objective To compare the diagnostic value of ultrasound and liver biopsy in the diagnosis of chronic hepatitis B. Methods Eighty patients with chronic hepatitis B received ultrasound and liver biopsy and compared the diagnostic results of the two methods. Results According to the pathological diagnosis of liver biopsy, 16 (20.00%) patients with cirrhosis, 28 (35.00%) patients with mild chronic hepatitis B and 36 (45.00%) patients with moderate-severe chronic hepatitis B were diagnosed by ultrasonography , Normal 5 (6.25%), liver cirrhosis 17 (21.25%), mild chronic hepatitis B patients 26 cases (32.50%), moderate and severe chronic hepatitis B patients 32 cases (40.00% Biopsy pathological diagnosis results, the difference was not statistically significant (P> 0.05). The sensitivity of ultrasonic diagnosis was 93.75% and the accuracy was 87.50%. Conclusions Liver biopsy can accurately reflect the nature and extent of lesions, which can be used as the gold standard for clinical diagnosis of chronic hepatitis B. In the clinical examination of chronic hepatitis B, the application of ultrasonic diagnosis is highly sensitive and accurate and can effectively avoid misdiagnosis and Misdiagnosis, can be used as the first choice of noninvasive examination of chronic hepatitis B.