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目的：为了探讨Ｇｒａｖｅｓ’甲亢患者治疗前、治疗后其血清ＴＴ３ 、ＴＴ４ 与可溶性白细胞介素－ ２受体（ＳＩＬ－ ２Ｒ） 水平的关系及临床意义。方法：用ＥＬＩＳＡ 法检测ＳＩＬ－ ２Ｒ。结果：治疗前ＴＴ３ 、ＴＴ４ 和ＳＩＬ－ ２Ｒ 均明显高于治疗后及正常对照组，ＳＩＬ－ ２Ｒ 与ＴＴ３ 、ＴＴ４ 呈正相关，分别γ＝ ０ ．４７（ Ｐ＜ ０ ．０５） 、γ＝ ０ ．６３（ Ｐ＜ ０ ．０５） 。结论：Ｇｒａｖｅｓ’甲亢患者血清ＳＩＬ－ ２Ｒ 水平变化，可作为一项免疫指标，监测其病情转归。
Objective: To investigate the relationship and clinical significance of serum TT3, TT4 and soluble interleukin 2 receptor (SIL-2R) levels in Graves’ hyperthyroid patients before and after treatment. Methods: SIL-2R was detected by ELISA. Results: Before treatment, TT3, TT4 and SIL-2R were significantly higher than those after treatment and normal control group. SIL-2R was positively correlated with TT3 and TT4, respectively, γ = 0. 47 (P <0 .05), γ = 0. 63 (P <0 .05). Conclusion: The serum levels of SIL-2R in patients with Graves’ hyperthyroidism can be used as an immune index to monitor the prognosis of patients with hyperthyroidism.