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钒作为一种工业毒物,其一般毒性早已为人们所了解。近年来对其致突变作用亦做了不少探讨[1],但对其诱发体内细胞染色体畸变的研究国内少有报道。我们通过染色体急性畸变试验研究了五氧化二钒(V2O5)对小鼠骨髓细胞染色体畸变率的影响,并对染毒后不同时间染色体畸变
Vanadium, an industrial poison, has long been known for its general toxicity. In recent years, its mutagenicity has also made a lot of discussion [1], but its induced cell chromosome aberrations in vivo rarely reported. We investigated the effects of vanadium pentoxide (V2O5) on chromosome aberration in mouse bone marrow cells by acute chromosome aberration test and analyzed the chromosomal aberrations