肝硬化钠潴留的重新估价

• 作 者: Murray Epstein 李希舜
• 出 处: 国外医学(消化系疾病分册)
• 发表日期: 1986年04期
• 关键词: 钠潴留 尿钠 全身浮肿 肾前性 肾功能不全 血浆醛固酮 肾性 安体舒通 肾素 介体

严重肝病时常伴有肾功能不全、钠潴留,患者因出现腹水及全身浮肿而就医.以往曾对肝病时肾对钠处理作了不少研究,但总是围着钠的“不足”与“过剩”两种学说.特别注意到引起肾性钠潴留的肾前性刺激及各种神经、内分泌介体的作用.因此,对其机理始终不能阐明.

Severe liver disease is often accompanied by renal insufficiency, sodium retention, patients with asymptomatic and systemic edema and seek medical treatment. In the past had a lot of research on sodium treatment of liver disease kidney, but always around the sodium “Excess ” two kinds of doctrine.Particular attention to cause prerenal renal stimulation of renal sodium retention and a variety of nerve, endocrine mediators, therefore, its mechanism can not be elucidated.