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目的 :探讨第一次1 31 I治疗后甲亢未缓解患者的临床指标变化情况。方法 :比较了 4 8例甲亢未缓解患者1 31 I治疗前后的甲状腺功能生化检查 ,2 4h内摄1 31 I率峰值及甲状腺重量变化情况。结果 :1 31 I治疗前后TT3,TT4 ,TSH相对稳定 ,而1 31 I治疗后的摄1 31 I率峰值、甲状腺均较治疗前变小。结论 :1 31 I能回缩甲状腺 ,即使甲亢患者的临床症状未缓解 ;因1 31 I治疗后患者的摄1 31 I率峰值减低 ,说明敏感性可能降低 ,在计算第二次1 31 I治疗剂量时 ,要调整给予的吸收剂量
Objective: To investigate the changes of clinical indexes in patients with unresponsive hyperthyroidism after the first 131 I treatment. Methods: Forty-eight patients with hyperthyroidism were not relieved before and after 131 I treatment of thyroid function biochemical tests, within 24 hours of 131 I peak rate and thyroid weight changes. Results: The TT3, TT4 and TSH were relatively stable before and after 131 I treatment, while the peak value of 131 I after 131 I treatment was lower than that before treatment. CONCLUSIONS: 1 31 I regresses thyroid gland, even in patients with hyperthyroidism, whose clinical symptoms have not been alleviated; patients with 131 I treatment peaked at a reduced rate of 1 31 I, indicating that the sensitivity may be reduced. After calculating the second 131 I treatment Dose, to adjust the dose given