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目的:观察β受体阻滞剂在治疗心衰患者时对心室收缩功能的影响。方法:将安装起博器有心衰症状的左室收缩功能障碍的66例患者,起博频率调整为60次每分并随即分为两组,治疗组33例在接受ACEI或ARB,氨体舒通治疗稳定的基础上加用β受体阻滞剂治疗;对照组33例接受ACEI或ARB,氨体舒通治疗;疗程为9个月,治疗前后行心脏彩色多谱勒检查,测量左室射血分数。结果:治疗组与对照组比较,治疗组显著提高平均左室射血分数。结论:在不改变心率的条件下,β受体阻滞剂在治疗心衰患者时可维持心室收缩功能。
Objective: To observe the effect of β-blockers on ventricular systolic function in the treatment of patients with heart failure. Methods: Sixty-six patients with pacemaker dysfunction with left ventricular systolic dysfunction were divided into two groups according to their frequency of poker. They were divided into two groups. The treatment group received 33 patients with ACEI or ARB, The patients in the control group received ACEI or ARB and amifostine. The course of treatment was 9 months. The heart color Doppler echocardiography was performed before and after treatment, and the left Room ejection fraction. Results: Compared with the control group, the treatment group significantly increased the average left ventricular ejection fraction. CONCLUSIONS: Beta-blockers maintain ventricular systolic function in patients with heart failure without changing heart rate.