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目的:研究早期尿激酶溶栓法应用于临床治疗急性心肌梗死的治疗效果,以期为今后临床实践提供参考依据,提高对急性心肌梗死的治疗水平。方法:以我院收治的60例急性心肌梗死患者为研究对象,根据临床治疗方案的不同将60例患者分为对照组与观察组,对照组采用临床常规治疗,观察组采用尿激酶溶栓法治疗,比较2组患者的再通率,及观察组不同时间进行治疗的再通率,分析早期尿激酶溶栓法治疗急性心肌梗死的临床疗效。结果:观察组冠脉再通率明显高于对照组(P<0.05);观察组3h内进行溶栓治疗患者的再通率为92.3%,3~6h再通率为70.0%,6~12h再通率为28.6%,三者比较差异有统计学意义(P<0.05)。结论:早期尿激酶溶栓法应用于临床治疗急性心肌梗死的治疗效果较好,能够有效提高急性心肌梗死患者冠脉再通率,提高患者的生存质量,对降低病死率具有重要的意义,值得在临床实践中广泛应用。
Objective: To study the therapeutic effect of early urokinase thrombolysis in clinical treatment of acute myocardial infarction, in order to provide reference for future clinical practice and improve the treatment of acute myocardial infarction. Methods: Sixty patients with acute myocardial infarction admitted to our hospital were studied. Sixty patients were divided into control group and observation group according to the different clinical treatment plans. The control group was treated with routine clinical treatment. The observation group was treated with urokinase thrombolysis The recanalization rates of two groups were compared, and the recanalization rate of the treatment group at different time was compared. The clinical efficacy of early urokinase thrombolysis in the treatment of acute myocardial infarction was analyzed. Results: The rate of coronary recanalization in the observation group was significantly higher than that in the control group (P <0.05). The recanalization rate was 92.3% in the observation group within 3 hours after thrombolysis, 70.0% in 3 to 6 hours and 6 to 12 hours The recanalization rate was 28.6%, the difference between the three was statistically significant (P <0.05). Conclusion: The early urokinase thrombolytic therapy is effective in clinical treatment of acute myocardial infarction. It can effectively improve the coronary recanalization rate and improve the quality of life in patients with acute myocardial infarction, which is of great significance to reduce the mortality rate. It is worth Widely used in clinical practice.