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基于行波介电泳原理,分析了电场强度和Clausius-Mossoti(C-M)因子的虚部对行波介电泳力的影响。对4种不同形状电极的电场强度分布进行了仿真建模,结果表明半圆形电极阵列有较好的传输特性,并建立了半圆形电极阵列在行波作用下的电场模型。以行波介电泳力的复数表达式为基础,得出了C-M因子虚部随频率的变化曲线。设计加工了基于半圆形电极阵列的细胞分离微流体芯片,基于行波介电泳原理,对金黄色葡萄球菌细菌进行了分离实验。通过对比分析,实验结果与仿真结果具有较好的一致性。因此,利用行波介电泳力,半圆形电极阵列能够有效地对细菌进行传输分离。
Based on the principle of traveling wave dielectric dielectrophoresis, the influence of the electric field and the imaginary part of the Clausius-Mossoti (C-M) factor on the traveling-wave dielectrophoretic force is analyzed. The electric field intensity distributions of four different shapes of electrodes were simulated. The results show that the semicircular electrode array has good transmission characteristics and the electric field model of semicircular electrode array under the action of traveling wave is established. Based on the complex expression of traveling wave dielectrophoretic force, the imaginary part of C-M factor with frequency is obtained. The cell separation microfluidic chip based on semicircular electrode array was designed and processed. The staphylococcus aureus bacteria were isolated based on the principle of traveling wave dielectrophoresis. Through comparative analysis, the experimental results and simulation results have good consistency. Therefore, the use of traveling wave dielectrophoretic force, semi-circular electrode array can effectively transfer bacteria separation.