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心律失常是影响肺动脉高压患者病死率的重要因素。目前认为肺动脉高压患者发生心律失常的因素包括心脏自律性改变、心脏复极化延迟导致QT间期延长、右心室心肌缺血等。室上性心动过速直接导致肺动脉高压患者预后不良。肺动脉高压患者室性心律失常少见,心动过缓是其强烈的死亡预测因子。本文对肺动脉高压患者出现不同心律失常的研究进展作一综述,旨在阐明肺动脉高压与心律失常的关系。
Arrhythmia is an important factor affecting the mortality of patients with pulmonary hypertension. At present, the factors that cause arrhythmia in patients with pulmonary hypertension include changes in cardiac autonomic changes, delayed QT prolongation caused by delayed repolarization of the heart and right ventricular myocardial ischemia. Supraventricular tachycardia directly leads to poor prognosis in patients with pulmonary hypertension. Ventricular arrhythmias are rare in patients with pulmonary hypertension and bradycardia is a strong predictor of death. This article reviews the research progress of different arrhythmia in patients with pulmonary hypertension to clarify the relationship between pulmonary hypertension and arrhythmia.