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[目的]探讨血清脂蛋白(a)[Lp(a)]、癌胚抗原(CEA)联合检测对肺癌的意义。[方法]测定82例肺癌患者的CEA、血清脂蛋白Lp(a)的水平并和健康对照组比较。[结果]肺癌组Lp(a)、CEA的水平分别为(362±141)mg/L和(34.92±15.6)ng/ml,明显高于对照组(P<0.01)。二者检测对肺癌早期诊断有一定意义,二者联合检测使肺癌诊断准确性、敏感性、特异性均有很大提高。[结论]二项血清学指标联合检测对肺癌的辅助诊断有重要临床意义。
[Objective] To investigate the significance of combined detection of serum lipoprotein (a) [Lp (a)] and carcinoembryonic antigen (CEA) in lung cancer. [Method] The levels of CEA and serum lipoprotein Lp (a) in 82 patients with lung cancer were determined and compared with those in healthy controls. [Results] The levels of Lp (a) and CEA in lung cancer group were (362 ± 141) mg / L and (34.92 ± 15.6) ng / ml respectively, which were significantly higher than those in control group (P <0.01). Both detection of lung cancer early diagnosis has a certain significance, the two joint detection of lung cancer diagnosis accuracy, sensitivity, specificity have greatly improved. [Conclusion] The combined detection of two serological markers has important clinical significance in the diagnosis of lung cancer.