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目的探讨伪膜性肠炎(PMC)的临床诊断及治疗。方法回顾性分析总结我院近期诊治的21例PMC的临床诊断及治疗资料。结果21例病人均在使用广谱抗生素过程中出现腹泻,并伴有腹痛、腹胀、发热及白细胞升高等现象。16例接受结肠镜检查,镜下显示病变主要累及远端结肠,大部分病人内镜下有较典型的改变。结论应用抗生素后若出现腹泻应考虑本病的可能。结肠镜检查是一快速而可靠的诊断方法。停用原抗菌素、口服甲硝唑或万古霉素是治疗PMC的有效方法。
Objective To investigate the clinical diagnosis and treatment of pseudomembranous enteritis (PMC). Methods The clinical diagnosis and treatment data of 21 cases of PMC diagnosed and treated in our hospital were retrospectively analyzed. Results All 21 patients had diarrhea during the course of using broad-spectrum antibiotics, accompanied by abdominal pain, bloating, fever and leukocytosis. Sixteen patients underwent colonoscopy. The lesions mainly involved the distal colon under the microscope. Most patients underwent endoscopic surgery with typical changes. Conclusion The use of antibiotics if diarrhea should consider the possibility of this disease. Colonoscopy is a quick and reliable diagnostic method. Discontinuation of the original antibiotics, oral metronidazole or vancomycin is an effective method of treatment of PMC.