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目的：比较中西医结合疗法和单纯西医药疗法治疗重症肾病综合征（ＳＮＳ）的疗效。方法：４０ 例ＳＮＳ患者随机分为治疗组（２０ 例，采用中西医结合治疗）和对照组（２０ 例，采用单纯西药治疗），比较２ 组患者临床疗效。结果：治疗组缓解率（９５．０％ ）、开始达到缓解的时间〔（２７．０±９．７）日〕、１ 年内复发率（１０．５％ ）及激素不良反应发生率（３５．０％ ）均明显优于对照组〔８０．０％ 、（３７．９±８．９）日、１８．８％ 和６５．０％ 〕，Ｐ均＜ ０．０５。结论：中西医结合治疗可提高ＳＮＳ缓解率，提前使ＳＮＳ缓解，降低复发率，减轻激素的不良反应，是治疗ＳＮＳ的较好疗法。
Objective: To compare the curative effect of combined traditional Chinese and western medicine therapy and western medicine therapy on severe nephrotic syndrome (SNS). Methods: Forty patients with SNS were randomly divided into treatment group (n = 20, treated with integrated traditional Chinese and western medicine) and control group (n = 20). The clinical effects of two groups were compared. Results: The response rate of the treatment group (95.0%), the time to the onset of remission 〔(27.0 ± 9.7) days〕, the recurrence rate within one year (10.5%) and the incidence of adverse reactions to glucocorticoid 0%) were significantly better than the control group (80.0%, (37.9 ± 8.9) days, 18.8% and 65.0%〕, P <0.05. Conclusion: Integrative Chinese and Western medicine can improve SNS remission rate, SNS mitigation in advance to reduce the recurrence rate and reduce the adverse effects of hormones, is a better treatment of SNS.