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作者报告6例恶性淋巴瘤均经脾切除诊断,其平均年龄49岁(30～61岁),男女各3例。6例中3例为单纯性牌肿大,其中1例有发热及体重减轻。另3例除脾肿大外其症状与血细胞减少有关,其中1例伴重症自身免疫性溶血性贫血,需大剂量强的松龙才能控制溶血。6例患者于术前均疑及淋巴瘤,但无肿大之表浅淋巴结可作活检,骨髓涂片及活检也不能确诊。手术无1例死亡,仅有2例有术后并发症。1例因出血需再次探查,另1例出现严重的血细胞减少及以后痊愈的胰瘘,后者在术前的中性白细胞数为0.4×10~9/L。无严重感染或因感染需再次入院者。所切除之脾脏平均重量1645 g(1200-2000 g)。淋巴瘤分型依据累及的腹腔淋巴结(4例)及脾脏浸润(2例)而定,其中4例为低度恶性的非何杰金氏淋巴瘤,均为滤泡中心性—原始中心细胞型(Kiel 分类),1例
The authors report 6 cases of malignant lymphoma were diagnosed by splenectomy, the average age of 49 years (30 to 61 years), 3 men and women. In 6 cases, 3 cases were simple swollen, in which 1 case had fever and weight loss. In addition to the other three cases of splenomegaly and its symptoms and cytopenia, of which 1 case of severe autoimmune hemolytic anemia, requiring large doses of prednisolone to control hemolysis. Six patients were suspected of preoperative lymphoma, but no enlarged superficial lymph nodes can be biopsy, bone marrow smear and biopsy can not be confirmed. No one died of surgery, only 2 cases had postoperative complications. One patient had to be probed again because of bleeding, the other one had severe cytopenia and subsequent recovery of the pancreatic fistula. The number of preoperative neutrophils was 0.4 × 10 ~ 9 / L. No serious infection or re-admission due to infection. The excised spleen has an average weight of 1645 g (1200-2000 g). Lymphomas were classified according to the involved celiac lymph nodes (4 cases) and splenic infiltrates (2 cases), of which 4 cases were low-grade non-Hodgkin’s lymphoma, all of which were follicular central-primitive central cell type (Kiel classification), 1 case