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目的:探讨桂林西瓜霜对宫颈糜烂组织细胞的影响。方法:将160例宫颈糜烂患者随机分为观察组和对照组,观察组用桂林西瓜霜喷敷宫颈糜烂面;对照组采用bFGF-胶原蛋白海绵外敷。光学显微镜下观察两组治疗前后的黏膜上皮细胞增生、炎细胞浸润、间质成纤维细胞增生情况。结果:观察组采用的桂林西瓜霜对鳞状上皮细胞增生、炎性细胞减少、肉芽组织及成纤维细胞形成、血管新生等有促进作用。经组织细胞病理形态学积分差比较,观察组对宫颈组织被覆上皮完好率高于对照组,经积分差u检验(P<0.05)差异有统计学意义;成纤维细胞增生积分差经u检验(P>0.05)差异无统计学意义。结论:桂林西瓜霜具有消炎抗菌、促进糜烂面愈合的作用。
Objective: To investigate the effect of Guilin watermelon cream on cervical erosion cells. Methods: 160 cases of cervical erosion were randomly divided into observation group and control group, the observation group with Guilin watermelon cream spraying cervical erosion surface; the control group with bFGF-collagen sponge. Under optical microscope, the proliferation of mucosal epithelial cells, infiltration of inflammatory cells and proliferation of mesenchymal fibroblasts were observed before and after treatment. Results: Guilin watermelon cream used in the observation group promoted the proliferation of squamous epithelial cells, inflammatory cells, formation of granulation tissue and fibroblasts, angiogenesis and so on. The pathological morphology of the difference between the histopathological difference, the observation group of cervical tissue epithelium intact rate was higher than the control group, by the difference between the difference u test (P <0.05), the difference was statistically significant; fibroblast proliferation difference by the u test P> 0.05) the difference was not statistically significant. Conclusion: Guilin watermelon cream has anti-inflammatory and anti-bacterial effects and promotes the healing of erosion surface.