论文部分内容阅读
本文综述有关郎罕细胞(LC)在抗病毒感染中的免疫作用。研究表明LC系单核巨噬细胞系统中Ia抗原(+)的特殊亚群,但在结构和功能上与巨噬细胞有一定差异。体外实验证实LC能呈递病毒抗原给T细胞,并诱导它发生增殖反应;体内研究提示局部LC和其他免疫细胞配合,给皮肤或粘膜提供免疫监视功能。文中对研究LC在机体抗病毒感染中的意义进行了讨论。
This review summarizes the immunogenicity of Langerhans cells (LC) in antiviral infections. Studies have shown that LCs are a distinct subset of Ia antigens (+) in the monocyte-macrophage system, but differ in structure and function from macrophages. In vitro experiments confirmed that LC can present viral antigens to T cells and induce its proliferative response; in vivo studies suggest that local LC and other immune cells cooperate to provide immune surveillance to the skin or mucous membranes. This article discusses the significance of LC in the antiviral infection of the body.