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检测了56例甲型和乙型病素性肝炎患者血清可溶性白细胞介素-2受体(sI1-2R)水平。结果与对照组相比除乙肝病毒携带者外,其余患者血清sI1-2R水平均增高,sI1-2R水平与谷丙转氨酶、黄疸指数呈正相关。乙肝患者病毒复制活跃者sI1-2R水平升高亦较明显。本文表明,血清sI1-2R水平可作为临床病情监测和预后判断的一项指标。
Serum soluble interleukin-2 receptor (sI1-2R) levels were measured in 56 patients with type A and B viral hepatitis. Results Compared with the control group, the serum levels of sI1-2R in all the patients except the hepatitis B virus carriers were increased. The levels of sI1-2R were positively correlated with the indices of alanine aminotransferase and jaundice. Hepatitis B virus replication in active sI1-2R levels were also more obvious. This article shows that serum sI1-2R levels can be used as an indicator of clinical condition monitoring and prognosis.