Synthesis and antibacterial activity of C-2(S)-substituted pleuromutilin derivatives

• 出 处: 中国化学快报：英文版
• 发表日期: 2010年5期
• 关键词: SYNTHESIS Pleuromutilin C-2(S)-substituted ANTIMICROBIAL ACTIVITY SynthesisPleur

In order to probe the effect of C-2(S)-substituted groups in the antibacterial activity,a series of novel C-2(S)-substituted pleuromutilin analogues of SB-225586 were synthesized and evaluated for their in vitro antibacterial activity.The results of antib