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目的:研究中西医结合治疗对鼻咽癌生存质量的影响。方法:243例鼻咽癌患者,分为2组。对照组给予常规放化疗;治疗组在对照组治疗基础上加用辨证中药方,辨为1痰瘀热毒,津液耗伤型,2气阴两虚,痰瘀内结型。通过生存质量量表(EORTC QLQHN-30量表)来调查中西医结合治疗对鼻咽癌无瘤生存者的生存质量影响。结果:2组治疗后3、6月功能领域、症状领域、总体健康比较,差异均有统计学意义(P<0.05),治疗组优于对照组;而经济困难项目比较,差异无统计学意义(P>0.05)。2组治疗后12月、18月症状领域、总体健康比较,差异均有统计学意义(P<0.05),治疗组优于对照组;而在功能领域、经济困难项目方面比较,差异无统计学意义(P>0.05)。结论:中医药在减轻鼻咽癌放化疗后副反应方面有明显优势,可通过对机体进行整体调节,从而提高生存质量。
Objective: To study the effect of integrated traditional Chinese and western medicine on the quality of life of nasopharyngeal carcinoma. Methods: 243 patients with nasopharyngeal carcinoma were divided into two groups. The control group was treated with radiotherapy and chemotherapy. The treatment group was treated with the traditional Chinese medicine prescription on the basis of the control group, identified as phlegm and blood stasis, toxic and wasting type, 2 Qi and Yin Deficiency, phlegm and blood stasis. Quality of life scale (EORTC QLQHN-30 scale) to investigate the combination of traditional Chinese and Western medicine treatment of cancer-free survival of patients with nasopharyngeal quality of life. Results: There were significant differences in functional area, symptom area and overall health between the two groups after 3 and 6 months of treatment (P <0.05), and the treatment group was better than the control group; however, the difference was not statistically significant (P> 0.05). The difference between the two groups was statistically significant (P <0.05), the treatment group was better than the control group in symptom field and overall health at 12 and 18 months after treatment, but there was no significant difference in the functional areas and economic difficulties Significance (P> 0.05). Conclusion: Traditional Chinese medicine has obvious advantages in alleviating side effects after radiotherapy and chemotherapy of nasopharyngeal carcinoma, and can improve the quality of life through the overall regulation of the body.