论文部分内容阅读
目的:分析1988—2004年河南省林州市人群胃癌的生存率及不同时期的变化,评估当地胃癌二级预防及临床诊治的水平。方法:从林州市肿瘤登记处提取1988—2004年全部的胃癌发病和死亡个案记录,剔除重复和仅有死亡证明书(death certificate only,DCO)的病例。计算该地区的去肿瘤死因寿命表,并与胃癌发病死亡数据相链接。采用现时生存分析(period survival analysis)方法计算1990—1994年、1995—1999年和2000—2004年这3个时期的胃癌5年观察生存率和相对生存率,并绘制相对生存曲线。结果:林州市3个时期的胃癌5年相对生存率分别为26.66%、32.01%和40.43%,呈逐年上升趋势。男性患者的生存率要高于女性。前2个时期的贲门癌生存率要高于非贲门胃癌,而在2000—2004年则低于非贲门胃癌。结论:林州市人群胃癌生存率自20世纪90年代起逐渐提高,反映了当地胃癌二级预防及临床诊疗水平的不断提高。
OBJECTIVE: To analyze the changes of gastric cancer survival rate and different periods in the population from 1988 to 2004 in Linzhou City of Henan Province, and to evaluate the secondary prevention and clinical diagnosis and treatment of local gastric cancer. Methods: All cases of gastric cancer incidence and death from 1988 to 2004 were extracted from the Linzhou Cancer Registry, and cases of repeated and death certificate only (DCO) were excluded. Calculate the life expectancy of cancer in the area, and link with the incidence of gastric cancer death data. The 5-year survival rates and relative survival rates of gastric cancer in 1990-1994, 1995-1999 and 2000-2004 were calculated by the period survival analysis method, and the relative survival curves were drawn. Results: The 5-year relative survival rates of gastric cancer in three periods in Linzhou City were 26.66%, 32.01% and 40.43% respectively, showing an upward trend year by year. Male patients have higher survival rates than women. The first two periods of cardia cancer survival rate was higher than non-cardia gastric cancer, but in 2000-2004 was lower than non-cardia gastric cancer. Conclusion: The survival rate of gastric cancer in Linzhou population has gradually increased since the 1990s, reflecting the continuous improvement of the secondary prevention and clinical diagnosis and treatment of local gastric cancer.