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在几种肾脏病模型中线粒体损伤会导致肾功能异常,但线粒体损伤是否与人类高血压相关仍不明确。死亡细胞释放的线粒体基因片段被认为是线粒体损伤的标志。该研究假设高血压与尿线粒体DNA拷贝数增加有关。研究人员在原发性高血压(n=25)、肾血
Mitochondrial damage can lead to renal dysfunction in several kidney disease models, but it remains unclear whether mitochondrial damage is associated with hypertension in humans. Mitochondrial gene fragments released by dead cells are thought to be markers of mitochondrial damage. The study hypothesized that hypertension is associated with increased urinary mitochondrial DNA copy number. Researchers in essential hypertension (n = 25), renal blood