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为了探讨用砷剂Melasoprol治疗罗德西睡眠病时并用强的松以防止并发症的作用,作者在赞比亚的某医院对36例查见罗德西锥虫的患者,分两组(每组18例)进行了治疗观察。一组从确诊日开始,即给予强的松治疗,成人量每次10毫克,儿童为5毫克,一日3次,至Melasoprol最后一针注射完毕后一周为止。另一组则不给强的松。所有患者均有脑膜炎的症状,在开始用Melasoprol治疗前的1、3及5天,均先后分别静脉注射苏拉明0.25克、0.25克和0.5克(儿童酌减)。用胂剂治疗前先纠正电解质的紊乱,血色素
In order to investigate the role of prednisone in the prevention of complications during treatment of Rhodesian sleep disorder with arsenic dose of Melasoprol, 36 patients in the same hospital in Zambia were challenged with Trypanosoma rhodesi in two groups (18 Cases) were treated for observation. One group started prednisone treatment with prednisone 10 mg daily for adults and 5 mg for children three times daily until one week after the last shot of Melasoprol. The other group does not give strong pine. All patients had meningitis symptoms. Suracetam was administered intravenously at 0.25, 0.25 and 0.5 g (for children) intravenously one, three and five days prior to initiation of Melasoprol treatment. Arsine treatment before correction of electrolyte disorders, hemoglobin