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目的探讨不稳定型心绞痛的临床治疗效果。方法回顾本院2006年12月至2009年6月采用阿托伐他汀治疗不稳定性心绞痛患者70例。结果治疗组中显效24例,有效9例,无效2例,总有效率94%;对照组中有效20例,有效6例,无效9例,总有效率72%。治疗组疗效优于对照组,差异有显著性(P<0.05)(见表1)。无不良反应,肝、肾功能均无明显变化,未出现明显肌痛、无力及转氨酶、肌酶升高等不良反应。结论阿托伐他汀治疗不稳定型心绞痛可明显改善血脂正常UA患者的临床症状,安全可靠、疗效显著。具有临床疗效好、毒副作用小,患者易耐受等优点,值得临床应用。
Objective To investigate the clinical effect of unstable angina pectoris. Methods From December 2006 to June 2009 in our hospital, 70 patients with unstable angina were treated with atorvastatin. Results In the treatment group, 24 cases were markedly effective, 9 cases were effective, 2 cases were ineffective, and the total effective rate was 94%. In the control group, 20 cases were effective, 6 cases were effective, 9 cases were ineffective and the total effective rate was 72%. The treatment group than the control group, the difference was significant (P <0.05) (Table 1). No adverse reactions, no significant changes in liver and kidney function, no obvious muscle pain, weakness and aminotransferase, muscle enzymes and other adverse reactions. Conclusion Atorvastatin treatment of unstable angina pectoris can significantly improve the clinical symptoms of patients with normal blood lipids, safe and reliable, the effect is significant. With good clinical efficacy, side effects, patient tolerance and other advantages, it is worth clinical application.