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多发性硬化(multiple sclerosis,MS)是以中枢神经系统炎症性脱髓鞘为主要病理改变的自身免疫性疾病,其主要临床特点为病灶的空间和时间多发性。目前,临床上对MS尚无特效治疗药物,西医主要采用激素、免疫抑制剂等药物治疗,中医主要采用辨证论治的方法加以治疗。根据MS不同的临床表现,中医将MS归属为“痿证”、“痹证”范畴,认为该病病位在“脑与髓”。中医理论认为“肾虚”为本病的根本病因,由于肾主骨生髓,髓汇于脊柱为脊髓、汇于脑为脑髓,在总结前人研究的基础上,从肾虚为本的角度探讨补肾药物对多发性硬化的治疗作用。
Multiple sclerosis (MS) is an autoimmune disease whose main pathological changes are inflammatory demyelination in the central nervous system. Its main clinical feature is the multiple spatial and temporal lesions. At present, there are no effective therapies for MS in clinical practice. Western medicine mainly uses drugs such as hormones and immunosuppressants. TCM is mainly treated by syndrome differentiation and treatment. According to the different clinical manifestations of MS, Chinese medicine will MS belong to “atrophy syndrome”, “Arthralgia” category, that the disease is located in the “brain and marrow.” According to the theory of traditional Chinese medicine, “kidney deficiency” is the fundamental cause of this disease. Because of the marrow of the kidney, bone marrow is the spinal cord in the spine and converges to the brain. On the basis of summarizing the previous studies, To explore the therapeutic effect of kidney-invigorating drugs on multiple sclerosis.