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本文报告经直肠滴入抗结核药及其它药物综合治疗婴幼儿及学龄前儿童结核病23例,取得显著效果。23例中,婴幼儿(4个月~3岁)21例,学龄前儿童(4~7岁)2例。未按种卡介苗者10例,无接种标记者8例。与结核病患者有接触史者16例。患结核病之前即有伴随疾病者20例。21例婴幼儿肺结核并发(肺段及肺叶)肺不张者8例,并发血原性及淋巴原性播散者12例(同时伴有结核性脑膜脑炎8例,原发综合征并发结核性脑膜脑炎1例)。23例中,病情严重者15例(伴有结核性脑膜脑炎3例分别于病后17、40及42天死亡)均不能口服药物,8例儿童病情好转后口服乙硫异烟胺或PAS引起呕吐。
This article reports the rectal infusion of anti-TB drugs and other drugs comprehensive treatment of infants and preschoolers, 23 cases of tuberculosis, and achieved remarkable results. Among the 23 cases, 21 were infants (4 months to 3 years old) and 2 were preschool children (4 to 7 years old). 10 cases of non-vaccinated BCG, 8 cases of non-vaccinated markers. Patients with history of exposure to tuberculosis in 16 cases. 20 cases of concomitant disease before suffering from tuberculosis. 21 cases of infantile pulmonary tuberculosis (pulmonary and lobular) atelectasis in 8 cases, with hematologic and lymphoid disseminated in 12 cases (accompanied by tuberculous meningitis in 8 cases, the primary syndrome complicated by tuberculosis Meningeal encephalitis in 1 case). Twenty-three of the 23 patients were in severe condition, and 15 patients (with tuberculous meningoencephalitis, 3 patients died at 17, 40 and 42 days after the illness) were not given oral medication. After 8 children were improved, they were given oral ethionamide or PAS Cause vomiting.