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NK细胞是功能异质性的群体,其亚群的分类方式至今无统一标准。根据NK细胞的表面标志、分泌细胞因子以及某些功能上的差异将其分为CD56~(bright)和CD56~(dim),NK1和NK2,A-NK和NA-NK等不同的亚群,这些亚群之间明显存在着表型和功能的差异,对NK细胞的研究有重要参考意义。
NK cells are functionally heterogeneous groups, and no sub-criteria has been found for the classification of their subsets. According to the surface markers of NK cells, secretion of cytokines and some functional differences, they are divided into different subsets of CD56 ~ (bright) and CD56 ~ (dim), NK1 and NK2, A-NK and NA- There is a clear difference in phenotype and function between these subpopulations, which is of important significance for the study of NK cells.