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在疟疾流行地区,5岁以下的儿童被认为是疟疾高发和易致死危险人群,但婴儿却有相对的抗疟原虫感染的保护力,出生后几个月内,婴儿较少感染疟原虫,一岁以下的儿童一般不患重症疟疾。这种先天性保护作用可能与经胎盘传递的母体恶性疟原虫特异性(P.f.- s)抗体有关。 1992年5月至1993年7月,在喀麦隆南部一中高度疟疾常年流行地区,作者将150名先后在产院分娩的产妇(4人分娩双胞胎)作为研究对象。征得产妇同意后,采集婴
In malaria-endemic areas, children under 5 years of age are considered to be at high risk of malaria and lethal deaths, but infants have relative protection against infection with malaria parasites. Females are less susceptible to malaria in the months following birth Children under the age are generally not suffering from severe malaria. This congenital protective effect may be related to placental transmission of P. falciparum-specific (P.f.-s) antibodies. Between May 1992 and July 1993, in an area endemic to mid-to-high malaria in southern Cameroon, 150 pregnant women (four births and twins) who gave birth in the maternity ward were studied. After obtaining the maternal consent, collect the baby