Efficacy and Safety of Nasal Administration of “Na-no-L-DOPA” Based on PLGA Nanoparticles

• 作 者: I.G. Kondrasheva T.A. Antipova
• 机 构: MoscowStateUniversityMoscow,ResearchCenterofMolecularDiagnostics&,TherapyMoscow
• 出 处: 工程(英文)(1947-3931)
• 发表日期: 2012年10期
• 关键词: Nanopaticls L-DOPA NASAL ADMINISTRATION Parkinson’s DISEASE NanopaticlsL-DOPANas

Inclusion of L-DOPA, the standard Parkinson’s disease medication, into polymeric particles (PLGA) results in optimization the drug metabolism and increasing its bioavailability, significantly increases of physical endurance, better coordination and lower