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目的探讨胃癌患者术前红细胞分布宽度(RDW)与临床病理特征及预后的关系。方法收集79例胃癌患者的临床资料,记录术前血常规中RDW值,分析术前RDW值与临床病理特征的关系;应用log-rank检验和Cox回归模型分析术前RDW与胃癌患者手术预后的关系。结果肿瘤的浸润深度、大小、临床分期与胃癌患者术前RDW值的高低有关(P<0.05或0.01)。术前RDW值高的胃癌患者术后无瘤生存期显著缩短(13.7 vs.19.1个月,P<0.01)。胃癌患者术前RDW值是影响胃癌患者术后无瘤生存期的一个独立危险因素(HR=1.855,95%CI:1.159~2.968,P<0.05)。结论胃癌患者术前RDW值有望成为预测胃癌患者术后预后的一个新的潜在指标。
Objective To investigate the relationship between preoperative red blood cell distribution width (RDW), clinicopathological features and prognosis of gastric cancer patients. Methods The clinical data of 79 patients with gastric cancer were collected. The preoperative RDW values were recorded. The relationship between preoperative RDW values and clinicopathological features was analyzed. The log-rank test and Cox regression model were used to analyze the preoperative RDW and surgical outcomes of gastric cancer patients. relationship. Results The depth, size and clinical stage of tumor invasion were related to the preoperative RDW values (P<0.05 or 0.01). Preoperative tumor survival in patients with high RDW values was significantly shorter (13.7 vs. 19.1 months, P<0.01). The preoperative RDW value of gastric cancer patients was an independent risk factor that affected the postoperative tumor-free survival of gastric cancer patients (HR=1.855, 95%CI:1.159~2.968, P<0.05). Conclusion Preoperative RDW value of gastric cancer patients is expected to be a new potential indicator to predict postoperative prognosis of gastric cancer patients.