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目的观察天麻素联合凯时治疗椎基底动脉供血不足的临床疗效。方法将84例椎基底动脉供血不足患者随机观察组和对照组,每组42例,治疗组给予天麻素联合凯时静滴,对照组仅予凯时静滴,疗程均为2周。观察两组治疗前后椎基底动脉的平均血流速度,评定两组的临床疗效,观察不良反应。结果治疗2周后,两组的椎基底动脉的平均血流速度均显著增高,而观察组的平均血流速度改善程度较对照组更优,同时,观察组的临床有效率为90.5%高于对照组的73.8%,组间差异有统计学意义,治疗过程中未见严重不良反应。结论天麻素联合凯时治疗椎基底动脉供血不足临床疗效确切,患者耐受良好,可在临床上推广应用。
Objective To observe the clinical efficacy of gastrodin combined with Kay when vertebrobasilar insufficiency clinical efficacy. Methods Eighty-four patients with vertebrobasilar insufficiency were randomized into observation group and control group, with 42 cases in each group. Gastrodin combined with Kai hour intravenous injection and control group only received Kay hour intravenous infusion. The course of treatment was 2 weeks. The average blood flow velocity of vertebrobasilar artery in both groups before and after treatment was observed. The clinical curative effect was evaluated and the adverse reactions were observed. Results After 2 weeks of treatment, the average blood flow velocity of vertebrobasilar artery in both groups increased significantly, while the average blood flow velocity in observation group improved more than that of control group. Meanwhile, the clinical effective rate in observation group was 90.5% The control group, 73.8%, the difference between the groups was statistically significant, no serious adverse reactions during the treatment. Conclusion Gastrodin combined with Kay when the treatment of vertebrobasilar insufficiency clinical curative effect is exact, the patient is well tolerated, and can be widely applied in clinic.