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目的分析奥曲肽与垂体后叶素治疗肝硬化上消化道出血患者疗效及安全性。方法 95例肝硬化上消化道出血患者,根据治疗方案分为对照组(40例)和研究组(55例)。对照组行垂体后叶素治疗,研究组行奥曲肽治疗,对比两组的疗效及止血时间。结果研究组止血时间、平均止血时间分别为(48.12±12.11)、(21.42±10.23)h,均显著短于对照组的(70.25±15.37)、(33.58±12.61)h,差异有统计学意义(P<0.05);研究组总有效率为94.55%,显著高于对照组的62.50%,差异具有统计学意义(P<0.05)。结论奥曲肽治疗肝硬化上消化道出血患者疗效及安全性显著,值得临床推广。
Objective To analyze the efficacy and safety of octreotide and pituitrin in the treatment of patients with cirrhosis and upper gastrointestinal hemorrhage. Methods A total of 95 patients with cirrhosis and upper gastrointestinal bleeding were divided into control group (40 cases) and study group (55 cases) according to the treatment plan. Control group pituitrin treatment, the study group octreotide treatment, the two groups compared the efficacy and bleeding time. Results The hemostatic time and mean hemostasis time in the study group were (48.12 ± 12.11) and (21.42 ± 10.23) h, respectively, which were significantly shorter than those in the control group (70.25 ± 15.37 and 33.58 ± 12.61) h, respectively P <0.05). The total effective rate of the study group was 94.55%, which was significantly higher than that of the control group (62.50%), the difference was statistically significant (P <0.05). Conclusion The efficacy and safety of octreotide in the treatment of patients with cirrhosis and upper gastrointestinal bleeding are significant and worthy of clinical promotion.