论文部分内容阅读
收集了我国部分地区HCV感染者血清363份,分别做了抗-HCVELISA和抗-HCV中和抑制试验。结果显示,我国不同地区(甚至同一地区不同民族)HCV感染者抗-HCV抑制率不同,而且中和抑制试验前后平均OD值的差异也有所不同,特别是西藏地区藏族和新疆地区维吾尔族分别只有3.2%和30.8%抗-HCV(+)血清能被同种多肽抗原所抑制,提示我国不同地区人群(甚至同一地区不同民族)HCV感染者的抗-HCV免疫反应性不同,并可能与不同地区的HCV变异性有关。
A total of 363 HCV sera were collected from some areas in China and anti-HCV ELISA and anti-HCV neutralization test were performed respectively. The results showed that the anti-HCV inhibitory rates of HCV infection in different areas (even from different nationalities of the same area) in China were different, and the difference of average OD value before and after the neutralization inhibition test was also different. Especially in Tibet and Xinjiang Uygur were only 3.2% and 30.8% of anti-HCV (+) serum can be allogeneic polypeptide antigen inhibition, suggesting that people from different regions of China (even from different ethnic groups in the same region) of HCV infection of anti-HCV immune reactivity and It may be related to HCV variability in different areas.