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在腎小体的血管极附近有腎小球旁器官(JuxtagIomerular apparatus)。它包括以下四部份:一、ε細胞(腎小球旁細胞,上皮样細胞),二、致密斑,三、Goormaghtigh氏細胞,四、Be-Cher氏門旁細胞群。早在1939年Goormaghtigh即考虑ε細胞可能是一种内分泌腺。1959年Marshall等发現ε細胞中的顆粒——腎小球旁顆粒(Juxtaglomerular granules)的溶解性与腎素(Renin高血压蛋白元酶)的相一致。1960年Bing等用显微解剖方法証明腎素存在于血管极附近。1959年、1960年Tobian等发現腎脏中腎素的含量和腎小球旁顆粒的多
There is a Juxtaglomerular apparatus near the very proximal renal artery. It includes the following four parts: a, ε cells (glomerular cells, epithelioid cells), two, dense plaques, three, Goormaghtigh cells, four, Be-Cher’s cell population. As early as 1939 Goormaghtigh that ε cells may be considered an endocrine gland. In 1959, Marshall et al. Found that the solubility of particles of Juxtaglomerular granules in ε cells was consistent with that of Renin (renin proteinase). In 1960, Bing et al used microscopic anatomical methods to prove that renin is present near the blood vessels. In 1959, Tobian et al found in 1960 that the renin content in the kidneys and the number of glomerular particles were much higher