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新生儿胆红素脑病是因血浆未结合胆红素透过血脑屏障沉积在基底节、海马等特殊神经核团而引起的急性中毒性脑病。诊断标准及相关定义:胆红素脑病的诊断与分期参考《实用新生儿学》[1]。胆红素对神经的毒性作用直接影响新生儿的致死、致残率。是临床上导致新生儿残疾的重要原因之一。其病死率高达50%～75%,经抢救后存活患儿中约75%～90%遗留严重的神经系统后遗症[2]。本文就我院近年来收治的37例新生儿胆红素脑病分析报告如下。
Neonatal bilirubin encephalopathy is due to plasma unbound bilirubin through the blood-brain barrier deposition in the basal ganglia, hippocampus and other special nerve nuclei caused by acute toxic encephalopathy. Diagnostic criteria and related definitions: bilirubin encephalopathy diagnosis and staging reference “Practical Neonatology” [1]. The toxic effects of bilirubin directly affect the neonatal mortality and morbidity. It is one of the most important causes of neonatal disability in clinic. The mortality rate as high as 50% to 75%, survived in the rescue of children about 75% to 90% of the serious legacy of the nervous system sequelae [2]. This article on my hospital admitted in recent years, 37 cases of neonatal bilirubin encephalopathy report is as follows.