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目的:探讨妊娠期糖代谢异常并发子痫前期的相关危险因素,以避免母婴严重并发症的发生。方法:选择同期妊娠期糖代谢异常产妇72例,根据患者病情将其分为A组和B组,A组为妊娠期糖代谢异产妇,B组为妊娠期糖代谢异常并发子痫前期产妇,比较两组产妇临床相关指标。结果:B组平均产次、孕前体重指数(BMI)、妊娠20周时平均收缩压(SBP)与平均舒张压(DBP)均显著高于A组(P<0.05);B组糖代谢异常诊断孕周显著早于A组(P<0.05);B组空腹血糖(FBG)、游离脂肪酸(FFA)、总胆固醇(TC)和甘油三酯(TG)水平均显著高于A组(P<0.05)。结论:对于生育次数较多、肥胖、基础血压较高、糖代谢异常诊断孕周较早以及FBG、FFA、TC和TG处于较高水平的妊娠期糖代谢异常产妇应加强监测,积极对症治疗,减少并发子痫前期的可能。
Objective: To investigate the related risk factors of preeclampsia with abnormal glucose metabolism in pregnancy in order to avoid the serious complications of mother and infant. Methods: Seventy-two pregnant women with abnormal glucose metabolism during the same period of gestation were divided into group A and group B according to the patient’s condition. Group A was the pregnant woman with glucose metabolism during pregnancy, group B with abnormal glucose metabolism during pregnancy and concurrent preeclampsia, The two groups of maternal clinical indicators were compared. Results: The average birth weight, body mass index (BMI) before pregnancy, mean systolic blood pressure (SBP) and mean diastolic blood pressure (DBP) at 20 weeks of gestation in group B were significantly higher than those in group A (P <0.05) (P <0.05). The levels of fasting blood glucose (FBG), free fatty acid (FFA), total cholesterol (TC) and triglyceride (TG) in group B were significantly higher than those in group A ). CONCLUSIONS: Women with abnormal glucose metabolism during pregnancy should be monitored intensively with obesity, high baseline blood pressure, early gestational weeks diagnosed with abnormal glucose metabolism, and high FBG, FFA, TC and TG levels, and aggressive symptomatic treatment. Reduce the possibility of concurrent preeclampsia.