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目的 采用医用橡胶导尿管被覆银后观察对ATCC 2 5 92 2大肠埃希氏菌、ATCC 2 5 92 3金黄色葡萄球菌、ATCC 2 785 3绿脓假单胞菌和ATCC 9372枯草杆菌黑色变种的体外杀菌作用。方法 将 1× 1 0 5/ml菌悬液与剪成 2cm长的表面被覆有含 1mg金属银的医用橡胶导尿管接触 ,在 8个时间梯度分别吸取菌悬液做菌落计数 ,同时用 5 %脱纤维羊血吸附残留银成份后 ,在摄氏 35℃的温度下培养 2 4小时 ,观察细菌生长结果。结果 被覆银导尿管对大肠埃希氏菌、绿脓假单胞菌和金黄色葡萄球菌具有很强的杀灭作用 ,且存在着一定的浓度、时间量效关系 ,对枯草杆菌黑色变种芽胞的杀灭效果不理想。结论 被覆银导尿管具有较高的临床应用价值 ,留置导尿管在 3天以上的病人 ,可减少长期留置普通导尿管引起泌尿道感染所带来的痛苦。
Objective To observe the effect of silver coated with medical rubber catheter on the black variants of ATCC 2 5 92 2 Escherichia coli, ATCC 2 5 92 3 Staphylococcus aureus, ATCC 2 785 3 Pseudomonas aeruginosa and ATCC 9372 Bacillus subtilis In vitro bactericidal effect. Methods The 1×105/ml bacterial suspension was contacted with a 2 cm long surface coated with a medical rubber urinary catheter containing 1 mg of metallic silver. The bacterial suspension was aspirated at 8 time gradients for colony counts, while 5 After the defibrinated sheep blood adsorbed the residual silver components, it was incubated at 35°C for 24 hours to observe the bacterial growth. Results The coated silver catheter had a strong killing effect on Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus, and there was a certain concentration and time dose-response relationship. Bacillus subtilis var. sp. The killing effect is not ideal. Conclusion The coated silver urinary catheter has a high clinical value. Patients with indwelling catheters for more than 3 days can reduce the pain caused by long-term indwelling common catheters causing urinary tract infections.